multiple organ dysfunction syndrome
Conditions
Interventions
HVHF Treatment group:Conventional treatment+HVHF (replacement fluid 4-6L/h) treatment.
Conventional treatment group:Conventional treatment
Sponsors
Xiamen Chang Gung Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Adult patients who meet the criteria for MODS (diagnostic criteria for MODS include simultaneous or sequential functional impairment or failure of two or more organs or systems in the respiratory, circulatory, liver, kidney, blood, gastrointestinal, metabolic, and central nervous systems, evaluated using a multi organ dysfunction rating scale with a score greater than or equal to 2 points). (2) Among them, 20 received routine treatment and 20 received routine treatment plus HVHF treatment.
Exclusion criteria
Exclusion criteria: (1) Relative contraindications for HVHF, such as inability to establish appropriate vascular access, allergies to extracorporeal blood pathways and other materials, severe coagulation dysfunction, and severe active bleeding, especially intracranial hemorrhage; (2) Patients or family members who refuse to undergo testing; (3) Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heparin binding protein;APACHE?;Hospitalization treatment expenses;hospital stay; | — |
Secondary
| Measure | Time frame |
|---|---|
| cardiac output, CO;cardiac index, CI;SVR;SVRI;SVV; | — |
Countries
China
Contacts
Public ContactXu Dongping
Xiamen Chang Gung Hospital
Outcome results
None listed