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Evaluation of bupivacaine liposomes in perioperative multimodal analgesia for bariatric surgery

Evaluation of bupivacaine liposomes in perioperative multimodal analgesia for bariatric surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500104979
Enrollment
Unknown
Registered
2025-06-26
Start date
2024-02-10
Completion date
Unknown
Last updated
2025-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain

Interventions

Treatment group:Preoperatively, bilateral transversus abdominis plane nerve blocks were performed with 10 ml of bupivacaine liposome + 20 ml of saline for a total of 30 ml on each side
Control subjects:Preoperatively, bilateral transversus abdominis plane nerve block was performed with 10 ml of 0.75% ropivacaine + 20 ml of saline for a total of 30 ml on each side

Sponsors

Department of Anesthesiology, Changzhou Second People's Hosptial Affiliated to Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with BMI >= 40 kg/m^2 2. Laparoscopic sleeve gastrectomy 3. ASA2-3 patients.

Exclusion criteria

Exclusion criteria: 1. Any complications (anaphylaxis or local anesthesia related complications) occurred during the block; 2. Failure or patient refusal; 3. Switch to open surgery or change the planned surgical protocol.

Design outcomes

Primary

MeasureTime frame
Analgesia (VAS) score during the first 72 hours postoperatively (24/48/72h);

Secondary

MeasureTime frame
Total intraoperative opioid use;Adverse events within three days of surgery;Time to first self-controlled analgesia;Total patient-controlled analgesic opioid consumption over time period (24/48/72h);Total postoperative non-opioid analgesic use;Evaluation of patient satisfaction with postoperative analgesia;Time to first postoperative ambulation;Post-operative hospitalization;

Countries

China

Contacts

Public ContactZhouquan Wu

Changzhou Second People's Hospital Affiliated to Nanjing Medical University

wuzhouquan2005@126.com+86 138 6102 3270

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 6, 2026