Cognitive dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1 Voluntary consent to participate in the study; 2 According to the POCD risk prediction model, the incidence of POCD at a high level ; 3 To accept elective non cardiac surgery; 4 The hospital stay before surgery is 5 days or more.
Exclusion criteria
Exclusion criteria: 1 Definitely diagnosed as senile dementia and preoperative MoCA score = 18; 2 Serious visual or hearing impairment, unable to complete cognitive function assessment; 3 The cognitive function assessment cannot be completed due to limb movement disorder; 4 The expected survival time is less than 1 month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of cognitive dysfunction 7 days after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes of cognitive function scores 7 days after operation;Changes of subjective and objective sleep quality 7 days after operation;Incidence of delirium 7 days after operation;Changes of cognitive function scores and incidence of cognitive dysfunction 30 days after surgery;Major complications and mortality 30 days after operation; | — |
Countries
China
Contacts
Peking University First Hospital