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Research on the Application of Comprehensive Intervention Program Based on Brain-Spinal Cord Neural Regulation in the Rehabilitation of Spinal Cord Injury

Research on the Application of Comprehensive Intervention Program Based on Brain-Spinal Cord Neural Regulation in the Rehabilitation of Spinal Cord Injury

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500104936
Enrollment
Unknown
Registered
2025-06-25
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal cord injury

Interventions

Six-character Formula training combined with percutaneous spinal cord electrical stimulation group:The electrode patches were placed in the C3-C4 spinal segments and the T9-T10 spinal segments . Accor
Transcranial direct current combined with electroencephalogram feedback group:The electroencephalogram feedback group included 20 minutes of transcranial direct current stimulation +20 minutes of elec

Sponsors

Tianjin Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed with spinal cord injury by clinical signs, X-ray, CT and MRI, meeting the B-D grade in the American Spinal Injury Association (ASIA) classification criteria; 2. Patients aged 18~65 years old, 1-3 months after spinal cord injury, and all vital signs are stable; 3. Presence of ventilation disorders: spirometry/predicted =4 points, which is consistent with neuropathic pain; 6. NRS score>=4 points; 7. Pain time>=3; 8. Maintain independent sitting >=30min.

Exclusion criteria

Exclusion criteria: 1. Previous respiratory diseases such as COPD and asthma; 2. Severe heart, liver and kidney diseases in the past; 3. Patients with severe brain trauma, thoracic and abdominal cavity injury, peripheral nerve injury, limb fracture and other conditions that affect neurological function examination; 4. Patients with spinal cord hemorrhage caused by myelitis, multiple sclerosis, spinal cord vascular malformation, spinal cord injury caused by neuraxial tumor; 5. Patients with brain diseases, history of brain injury, and intracranial metal implants; 6. Patients with severe cognitive dysfunction, such as dementia and Alzheimer's disease; 7. Patients with severe cardiovascular diseases, respiratory diseases, hematologic diseases, etc.

Design outcomes

Primary

MeasureTime frame
Maximal Inspiratory Pressure;Peak Volume of Inspiratory Flow Rate;Thickness of diaphragm;Lung function;Numeric rating scale scores;Hospital Anxiety and Depression Scale;Tenderness threshold;EEG;

Countries

China

Contacts

Public ContactXiaolei Chu

Tianjin Hospital, Tianjin

Chuxiaolei8@163.com+86 150 2209 6747

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026