Mild Cognitive Impairment
Conditions
Interventions
Active tDCS group:Anodal tDCS over the left dorsolateral prefrontal cortex (left DLPFC)
sham tDCS group:Sham tDCS over the left dorsolateral prefrontal cortex (left DLPFC)
Sponsors
Nanjing Brain Hospital
Eligibility
Sex/Gender
All
Age
55 Years to 67 Years
Inclusion criteria
Inclusion criteria: All participants were informed of the experimental procedures and objectives and provided written informed consent. Participants met the following requirements: Right-handedness (assessed using the Chinese Handedness Inventory); Normal or corrected-to-normal vision (visual acuity = 0.8); No history of long-term psychotropic medication use. For MCI participants, additional criteria applied: Subjective cognitive complaints; Montreal Cognitive Assessment (MoCA) score < 26 (with 1-point adjustment for <= 12 years of education; maximum score = 30); Clinical Dementia Rating (CDR) score < 1, excluding dementia diagnosis; Preserved basic activities of daily living.
Exclusion criteria
Exclusion criteria: Severe hearing/communication impairments or physical disabilities; Current use of psychotropic medications or alcohol dependence; Major neuropsychiatric disorders (e.g., severe dementia, major depressive disorder, schizophrenia); Organic brain diseases (e.g., encephalitis, traumatic brain injury); Voluntary withdrawal or inability to complete the study; Contraindications for tDCS: Cardiac pacemakers or intracranial metal implantsl; History of epilepsy or stroke; Poor compliance or tDCS intolerance; tDCS treatment within 3 months or prior adverse events; Clinical deterioration during the study period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| inhibitory control;working memory updating;selective attention; | — |
Countries
China
Contacts
Public ContactLuo Yuanrong
Nanjing Brain Hospital
Outcome results
None listed