Refractory Mycoplasma pneumoniae pneumonia in children
Conditions
Interventions
Refractory MPP group (RMPP group):None
Non-refractory MPP group (NRMPP group):None
Sponsors
Quzhou People Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Diagnostic criteria for MPP: (1) symptoms and signs suggestive of CAP, including fever, cough, abnormal auscultation of the lungs, and/or new infiltrates on chest x-ray; (2) positive for MP-IgM in a single serum (titer >=1:160); Double serum MP antibody titers increased 4-fold or more during the course of illness or positive MP-RNA test. Refractory mycoplasma pneumoniae pneumonia (RMPP): refers to children with MPP who have been treated with macrolide antimicrobials for 7 days or more, but still have persistent fever, exacerbation of clinical signs and lung imaging, and extrapulmonary complications Children who meet the above diagnostic criteria for MPP and are hospitalized with informed consent from their families.
Exclusion criteria
Exclusion criteria: 1. Positive test for other pathogens; 2. Have received glucocorticoids or immunosuppressive therapy before admission; 3. Primary/secondary immunodeficiency; 4. Children with congenital airway malformations, congenital heart disease, and pre-existing chronic respiratory diseases; 5. Hereditary metabolic diseases; 6. The medical record information is incomplete.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical presentation of the child;Laboratory tests;Peripheral blood neutrophil CD64;Radiographic findings;Differences between treatment and prognosis; | — |
Countries
China
Contacts
Public ContactYan Zheng
Quzhou People's Hospital
Outcome results
None listed