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A Randomized Controlled Trial of AAD Therapy for Promoting Diabetic Foot Ulcer Healing

A Randomized Controlled Trial of AAD Therapy for Promoting Diabetic Foot Ulcer Healing

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500104914
Enrollment
Unknown
Registered
2025-06-25
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetic Foot Ulcer

Interventions

MetF:Insulin+Metformin
GLP-1RAs:Insulin+GLP-1RAs
Control group:Insulin threrapy

Sponsors

Shanghai Fifth Peoople's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with lower limb ulcers due to type 2 diabetic foot.

Exclusion criteria

Exclusion criteria: 1.Those with concurrent acute diabetic complications; 2.Those with severe hepatic and renal insufficiency and cardiac insufficiency; 3.Those with severe infections in the respiratory tract, digestive tract, and urinary system; 4.Patients who are pregnant, breastfeeding, or planning to become pregnant; 5.Patients with type 1 diabetes and special types of diabetes.

Design outcomes

Primary

MeasureTime frame
Wound assessment of lower limb ulcers;

Secondary

MeasureTime frame
SASP-related factors (such as p21, IL-6, TGF-ß1, CCL2, etc.);The length of telomerase in white blood cells;

Countries

China

Contacts

Public ContactYang Min

Shanghai Fifth Peoople's Hospital

yangmin56789@163.com+86 21 24249503

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026