Low back pain
Conditions
Interventions
PDRN group:Intramuscular injection of 3 mL PDRN into the thoracolumbar fascia once a week for three consecutive weeks
home-based lumbar and back muscle exercises.
Placebo group:Intrathoracolumbar fascia injection of 3 ml of 0.9% sodium chloride injection once a week for three consecutive weeks
Sponsors
The First Affiliated Hospital of Air Force Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for myofascial low back pain; 2. Moderate to severe pain, with a Visual Analog Scale (VAS) score > =4; 3. Patients are aged between 18 and 65 years; 4. Duration of symptoms exceeds one month; 5. Patients have a thorough understanding of the study content, with good compliance and high level of cooperation; 6. Informed consent has been signed.
Exclusion criteria
Exclusion criteria: 1. Low back pain caused by any other reasons, including but not limited to lumbar disc herniation, lumbar spinal stenosis, ankylosing spondylitis, spinal tumors, spinal tuberculosis, spinal cord infections, etc.; 2. Patients with severe diabetes or drug allergies; 3. Patients with fever, upper respiratory tract infections, or other infectious diseases; 4. Patients with systemic diseases or organ dysfunction; 5. Patients with coagulation disorders or those taking anticoagulant medications; 6. Patients with infections of the injection site or surrounding soft tissues; 7. Patients currently using corticosteroids or undergoing other treatments that may affect the observation indicators of this study; 8. Patients with severe mental illness who cannot cooperate; 9. Pregnant or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analogue scale,VAS;Medical Outcom Study 36-Item Short-Form Health Survey, SF-36; | — |
Secondary
| Measure | Time frame |
|---|---|
| OswestryDisability Index, ODI ; | — |
Countries
China
Contacts
Public ContactGao bo
The First Affiliated Hospital of Air Force Medical University
Outcome results
None listed