Comparison of the effects of Ciprofol and Propofol induction on hemodynamics during the anesthesia Induction period in patients undergoing liver transplantation

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500104905

Enrollment

Unknown

Registered

2025-06-25

Start date

2025-07-01

Completion date

Unknown

Last updated

2025-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End-stage liver disease

Interventions

Group P (Propofol Group):anesthesia induction with propofol

Group C (Ciprofol Group):anesthesia induction with ciprofol

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Patients scheduled for liver transplantation in this hospital. 2.ASA classification Grade I - IV; 3.Aged 18-65 years, regardless of gender; 4.Able to communicate effectively and willing to participate in this study;

Exclusion criteria

Exclusion criteria: 1.Untreated stage 2 and stage 3 hypertension; 2.Known allergies to eggs, soy products, propofol, or ciprofol; 3.Other reasons that make the investigator believe the patient is not suitable for inclusion in the clinical trial;

Design outcomes

Primary

Measure	Time frame
The dosage of norepinephrine used during the anesthesia induction period.;	—

Secondary

Measure	Time frame
The average degree of fluctuation of systemic vascular resistance index during the anesthesia induction period.;The fluctuation of mean arterial pressure during the anesthesia induction period.;The maximum decrease in mean arterial pressure.;The average degree of fluctuation of the cardiac index during the anesthesia induction period.;Blood lactic acid levels during the anesthesia induction period;	—

Measure

Time frame

The average degree of fluctuation of systemic vascular resistance index during the anesthesia induction period.;The fluctuation of mean arterial pressure during the anesthesia induction period.;The maximum decrease in mean arterial pressure.;The average degree of fluctuation of the cardiac index during the anesthesia induction period.;Blood lactic acid levels during the anesthesia induction period;

—

Countries

China

Contacts

Public ContactYang lu

The First Affiliated Hospital,Sun Yat-sen University

yanglu6@mail.sysu.edu.cn+86 139 2950 8567

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026