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The effect of transcutaneous vagus nerve stimulation on the recovery of gastrointestinal function after laparoscopic non-gastrointestinal surgery

The effect of transcutaneous vagus nerve stimulation on the recovery of gastrointestinal function after laparoscopic non-gastrointestinal surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500104886
Enrollment
Unknown
Registered
2025-06-25
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative gastrointestinal dysfunction

Interventions

enter PACU2. Stimulation Parameters:frequency 25 Hz, pulse width 200 µs, 30 seconds on/30 seconds off, intensity set to the maximum amplitude tolerated by the patient, with continuous stimulation for
enter PACU2. Apply sham stimulation for 30 minutes each session: abort stimulation if the participant reports "tingling/pain"

Sponsors

The Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age 18–65 years old; 2. ASA I–III; 3. BMI 18–28 kg/m²; 4. Elective laparoscopic non-gastrointestinal surgery under general anaesthesia; 5. Agree to participate in this study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Implanted electrical stimulation devices (such as pacemakers or defibrillators); 2. Preoperative heart rate below 60 beats per minute; 3. Patients with airway hyperresponsiveness (asthma, COPD); 4. Diagnosed with chronic gastrointestinal inflammation; 5. Mental or neurological disorders; 6. Severe cardiovascular or cerebrovascular diseases, impaired liver or kidney function; 7. Skin infections or ulcers at the stimulation site, etc. 8. Long-term use of opioid medications 9. History of abdominal surgery and intestinal obstruction

Design outcomes

Primary

MeasureTime frame
The time of the first flatus after the surgery;

Secondary

MeasureTime frame
The time of the first defecation after the operation;Pain socre;Early Restoration Quality Score;Anxiety and depression scores;Sleep Quality Index;Postoperative incidence of nausea and vomiting;Intake,feeling nauseated,emesis,exam,and duration of symptoms scoring system;Gastrointestinal symptom score;Additional use of analgesic drugs after surgery;Intraoperative opioid dosage;

Countries

China

Contacts

Public ContactYin Qin

The Affiliated Hospital of Xuzhou Medical University

810780794@qq.com+86 138 1444 6826

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026