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A prospective controlled study on the microbiological diagnostic efficacy evaluation of targeted next-generation sequencing technology in sputum and bronchoalveolar lavage fluid specimens from patients with pneumonia

A prospective controlled study on the microbiological diagnostic efficacy evaluation of targeted next-generation sequencing technology in sputum and bronchoalveolar lavage fluid specimens from patients with pneumonia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500104885
Enrollment
Unknown
Registered
2025-06-25
Start date
2023-09-10
Completion date
Unknown
Last updated
2025-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pneumonia

Interventions

Observation group:NO

Sponsors

Nanbu People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.It meets the diagnostic criteria for community-acquired pneumonia/hospital-acquired pneumonia in China; 2. Agree to participate in the research and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Patients with tracheal intubation/tracheotomy; 2. Patients who are unable to cough up phlegm or remain without phlegm after being induced by phlegm; 3. Patients with contraindications for bronchoscopy; 4. Concurrent mental illness or cognitive dysfunction; 5. Refuse to sign the informed consent form.

Design outcomes

Primary

MeasureTime frame
The degree of consistency between sputum tNGS and BALFtNGS;—

Countries

China

Contacts

Public ContactFeng Xin

Nanbu People's Hospital

176141659@qq.com+86 177 3884 6635

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026