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Robot-Assisted Radical Prostatectomy with Delayed Dorsal Venous Complex (DVC) Ligation and Anterior Sphincter Reconstruction: A Single-Center, Randomized, Open-Label, Controlled Clinical Trial

Robot-Assisted Radical Prostatectomy with Delayed Dorsal Venous Complex (DVC) Ligation and Anterior Sphincter Reconstruction: A Single-Center, Randomized, Open-Label, Controlled Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500104873
Enrollment
Unknown
Registered
2025-06-25
Start date
2025-06-30
Completion date
Unknown
Last updated
2025-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prostate cancer

Interventions

Control Group:The control group underwent conventional RARP. The key surgical steps are briefly described as follows: 1. Following anesthesia induction and patient positioning, pneumoperitoneum was e
Novel-technique Group:The majority of surgical steps in the novel-technique group were similar to those in the control group, with the primary differences lying in the management of the ventral aspect
this higher insufflation pressure helps prevent most venous bleeding. Subsequently, the DVC was transected without prior suture ligation, and bleeding was observed. In most cases, only minimal bleedin

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Age 18-80 years. 2.Clinically diagnosed prostate cancer with tumor stage cT1-3a. 3.Scheduled to undergo Robot-Assisted Radical Prostatectomy (RARP). 4.No prior use of novel endocrine therapy. 5.No history of previous prostate surgery. 6.No history of urinary incontinence.

Exclusion criteria

Exclusion criteria: 1.Severe cardiovascular or circulatory disorders rendering patients unfit for surgery; 2.Pregnancy or lactation; 3.Documented history of epilepsy or psychiatric disorders; 4.Severe allergic predisposition; confirmed or suspected alcohol/drug addiction; 5.Inability to comprehend study requirements or adhere to follow-up protocols; 6.Deemed ineligible by investigators based on clinical judgment; 7.Patients undergoing secondary or subsequent surgeries; 8.Inability to participate in routine postoperative rehabilitation programs.

Design outcomes

Primary

MeasureTime frame
Short-term postoperative urinary continence rate;

Secondary

MeasureTime frame
Short term subjective perception of urinary control function;Postoperative instant urinary continence rate;Instant subjective perception of urinary control function;Surgery time;Surgery bleeding;Surgical complication occurrence rate;Conversion rate to S-DVC;Positive margin rate;

Countries

China

Contacts

Public ContactShudong Zhang

Peking University Third Hospital

zhangshudong@bjmu.edu.cn+86 156 1196 3326

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026