tumor
Conditions
Interventions
Control group:Anesthesia induction with 0.1 mg/kg, followed by equivalent-volume normal saline infusion until 1 hour pre-surgical conclusion
Low-dose Oxycodone Group:Anesthesia induction: oxycodone 0.1 mg/kg
maintenance infusion at 0.02 mg/kg/h until 1 hour before surgery completion
High-dose Oxycodone Group:Anesthesia induction: oxycodone 0.1 mg/kg
maintenance infusion at 0.04 mg/kg/h until 1 hour before surgery completion
Sponsors
Anqing Municipal Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 68 Years
Inclusion criteria
Inclusion criteria: 1.Patients with complete clinical data who are intended to undergo gynecologic hysteroscopic surgery; 2.The patient's age is 18-68 years old; ASA classification I-?; 3.NYHA Class I-II; 4.Body mass index (BMI) of 17-28 kg/m^2; 5.Clearly understand, voluntarily participate in the study and sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1.Individuals with a history of alcohol abuse or drug abuse; 2.Opioid-dependent individuals; 3.Patients with accompanying hearing and speech impairments are unable to cooperate with the examiner; 4.Patients with preoperative severe systemic diseases, such as neuropsychiatric disorders, paralytic ileus or acute abdomen, hepatic or renal insufficiency, uncontrolled hypertension, diabetes mellitus, or other organ dysfunction; 5.Recent history of acute upper respiratory tract infection or pulmonary infection; 6.patients during pregnancy or lactation; 7.Preoperative administration of sedatives or analgesics; 8.Those who are allergic to opioids and other anesthetic drugs; 9.The patient or their family members declined to participate in the study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The QoR-15 scale scores and sleep quality scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time Statistics Operation time;Postoperative adverse reactions and corrective treatment;Dosage of propofol, remifentanil, cisatracurium, and other adjuvant drugs;Visual Analogue Scale (VAS) Score and Ramsay Sedation Scale (RSS);Hemodynamic Indicators;Postoperative ventilation and defecation time; | — |
Countries
China
Contacts
Public ContactJu Xia
Anqing Municipal Hospital
Outcome results
None listed