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A prospective randomized controlled clinical study on the prediction of psychological improvement in patients with chronic obstructive pulmonary disease (COPD) after pulmonary rehabilitation intervention by blood eosinophils

A prospective randomized controlled clinical study on the prediction of psychological improvement in patients with chronic obstructive pulmonary disease (COPD) after pulmonary rehabilitation intervention by blood eosinophils

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500104796
Enrollment
Unknown
Registered
2025-06-24
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic obstructive pulmonary disease

Interventions

Rehabilitation group (RG):Pulmonary rehabilitation
Conventional treatment group (CG):Conventional treatment

Sponsors

Medical Ethics Committee of Chongqing Changshou District People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to No maximum

Inclusion criteria

Inclusion criteria: 1: Age >=40 years old; 2: According to the GOLD guidelines for diagnosing chronic obstructive pulmonary disease, the forced expiratory volume in one second/forced vital capacity (FEV1/FVC ratio) after inhaling bronchodilators is less than 70%; 3: The condition has deteriorated and stabilized (those with no deterioration of respiratory symptoms or acute exacerbation can tolerate relevant training).

Exclusion criteria

Exclusion criteria: 1: Patients who have undergone lung surgery within 3 months and have other lung diseases (asthma, pulmonary fibrosis, bronchiectasis, tuberculosis); 2: Arrhythmia, recent unstable angina pectoris attack or acute myocardial infarction, uncontrolled hypertension; 3: Active bleeding, unstable fractures, and movement difficulties caused by neuromuscular diseases; 4: Infectious diseases; 5: Severe cognitive impairment, abnormal mental behavior, lack of motivation, poor compliance and other reasons prevent cooperation with pulmonary rehabilitation.

Design outcomes

Primary

MeasureTime frame
6-minute walk test;mMRC;COPD Assessment Test;HADS-A/HDAS-D;Patient Health Questionnaire-9;Generalized Anxiety Disorder-7 item, GAD-7;Beck Depression Inventory;Beck Anxiety Inventory, BAI;

Countries

China

Contacts

Public ContactYejie Cheng

Chongqing Changshou District People's Hospital

838438470@qq.com+86 68310427

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026