The effect of inhalation of nebulized dexmedetomidine on pulmonary complications after single lung ventilation in children undergoing lobectomy

Effect of nebulized dexmedetomidine inhalation on postoperative pulmonary complications after children one-lung ventilation

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500104793

Enrollment

Unknown

Registered

2025-06-23

Start date

2025-07-01

Completion date

Unknown

Last updated

2025-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pulmonary complications after one-lung ventilation in children

Interventions

Control:Normal saline

Dexmedetomidine:Nebulized dexmedetomidine inhalation

Eligibility

Sex/Gender

All

Age

1 Years to 6 Years

Inclusion criteria

Inclusion criteria: Patients under 6 years old who undergo elective thoracoscopic segmentectomy or lobectomy, ASA grade 1-2;

Exclusion criteria

Exclusion criteria: History of asthma, acute upper respiratory or pulmonary infections, congenital heart disease, EF<50%;

Design outcomes

Primary

Measure	Time frame
Postoperative pulmonary complications;	—

Secondary

Measure	Time frame
Biochemical indicators of bronchoalveolar lavage fluid;Blood gas analysis result;Hemodynamic indicators: occurrence of hypotension and bradycardia; PACU sedation score;PACU stay time and hospitalization time;Parameters and indicators of ventilator;Oxygenation index;	—

Countries

China

Contacts

Public ContactZhang Pengbo

Xi'an Jiaotong University Second Affiliated Hospital

zhpbo@163.com+86 29 8767 9635

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026