Meets the criteria for the diagnosis of gastroesophageal reflux (Chinese guideline criteria) in the Rome IV. criteria (and) or functional dyspepsia (and) or irritable bowel syndrome
Conditions
Interventions
The observation group consisted of three functional gastrointestinal diseases (gastroesophageal reflux, functional dyspepsia, irritable bowel syndrome) and symptom overlapping group (overlapping diagn
Control group: A single group with symptoms of 3 functional gastrointestinal diseases (gastroesophageal reflux, functional dyspepsia, irritable bowel syndrome).:None
Sponsors
The People's Hospital of Baiyun District Guangzhou
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Meets the criteria for the diagnosis of gastroesophageal reflux (Chinese guideline criteria) in the Rome IV. criteria (and) or functional dyspepsia (and) or irritable bowel syndrome. 5.2 Inclusion Criteria: (1) Meet the above diagnostic criteria; 2. Age 18~70 years old; 3. Not receiving intestinal probiotic therapy in the past 1 month; 4. Those who have no cognitive impairment or communication impairment and can cooperate with the questionnaire; 5. Complete clinical data; 6. All patients were aware of the content of this study and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Acute digestive system diseases such as acute gastritis, gastric ulcer, and gastrointestinal bleeding; 2. Those with immunological and hematologic diseases; 3. Previous history of acute myocardial infarction or cerebrovascular accident (within 6 months) 4 Heart, lung, liver, kidney insufficiency and other underlying diseases; 5. Those with mental illness; 6. Lactating and pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gastrointestinal symptom score (PAGI–QOL),;Psychopsychiatric factors (HAMD, HAMA, PSQI score), ;Intestinal microbiota factors; | — |
Secondary
| Measure | Time frame |
|---|---|
| General demographic characteristics, ; | — |
Countries
China
Contacts
Public ContactPENG WEIQI
The People's Hospital of Baiyun District Guangzhou
Outcome results
None listed