Knee Osteoarthritis
Conditions
Interventions
Sponsors
The Second Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Age range: 50 - 80 years old, gender not restricted; (2) Diagnosed with end-stage osteoarthritis, Kellgren-Lawrence grade (KL) 3-4, standard conservative treatment for more than 6 months was ineffective; (3) Have undergone unilateral knee arthroplasty (TKA) surgery; (4) Within three months of the perioperative period, no joint cavity puncture or drug injection, no joint surrounding dressing, etc. were performed, and the infection risk assessment was low; (5) All surgeries were performed by doctors with a title of associate chief physician or above, with more than 100 TKA surgeries per year and having independently completed more than 300 such surgeries; perioperative care was implemented in accordance with the same joint replacement management norms; (6) Complete preoperative and postoperative blood routine tests, preoperative coagulation function, inflammatory indicators, blood sugar, lower extremity vascular color ultrasound and other examination and test data were available.
Exclusion criteria
Exclusion criteria: (1) Patients with bilateral knee osteoarthritis (OA) who underwent simultaneous bilateral total knee arthroplasty (TKA); (2) Patients with bilateral OA who received TKA surgery within a gap of less than 2 months consecutively; (3) Patients who received anticoagulant treatment due to concurrent cardiovascular or cerebrovascular diseases before the surgery; (4) Patients diagnosed with purulent infection of the knee joint through tissue culture or case diagnosis during or after the surgery; (5) Patients with a clear diagnosis of rheumatoid arthritis, gouty arthritis, or traumatic arthritis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total perioperative blood loss; | — |
Secondary
| Measure | Time frame |
|---|---|
| Western Ontario and McMaster Universities Osteoarthritis Index;Keen Society Score ;Hospital for Special Surgery Score;complications;blood routine ; | — |
Countries
China
Contacts
Public ContactZhang Yuan
The Second Affiliated Hospital of Army Medical University
Outcome results
None listed