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Clinical Investigation and Mechanistic Analysis of Donor Atherosclerotic Lesions and Transplant Renal Artery Stenosis

Clinical Investigation and Mechanistic Analysis of Donor Atherosclerotic Lesions and Transplant Renal Artery Stenosis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500104769
Enrollment
Unknown
Registered
2025-06-23
Start date
2025-06-30
Completion date
Unknown
Last updated
2025-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Transplant renal artery stenosis

Interventions

Retrospective study (TRAS group, non-TRAS group):None
Donor group:None
Prospective study (atherosclerotic plaque group, normal artery group):None

Sponsors

Southern Medical University Southern Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Kidney transplant recipients 1. Voluntarily sign the informed consent form; 2. Age>=18; 3. From January 2020 ~ June 2026, he was admitted to the Department of Organ Transplantation, Nanfang Hospital, Southern Medical University, for deceased donor kidney transplantation. Kidney transplant donors 1. Voluntarily sign the informed consent form; 2. Age>=18; 3. From January 2020 ~ June 2026, he or she will be admitted to Nanfang Hospital of Southern Medical University and voluntarily donate his body as a kidney transplant donor.

Exclusion criteria

Exclusion criteria: Kidney transplant recipients 1. Grafted renal artery stenosis in kidney transplant recipients within 5 days after kidney transplantation; 2. Kidney transplant recipients fail to function or die in the early stage after kidney transplantation; 3. Kidney transplant recipients who are judged by the investigator to be unsuitable to participate in this study. Kidney transplant donors 1. The kidney transplant donor has no remaining arterial specimens during the kidney transplantation process; 2. Kidney transplant donors who are judged by the investigator to be unsuitable to participate in this study.

Design outcomes

Primary

MeasureTime frame
Histopathological classification of aortic atherosclerotic plaques;Occurrence of Transplant Renal Artery Stenosis;

Countries

China

Contacts

Public ContactYun Miao

Southern Medical University Southern Hospital

miaoyunecho@126.com+86 20 61641786

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026