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The Value of the New FIGO Staging System in Prognostic Evaluation of Endometrial Cancer: A Bidirectional Cohort Study Based on NRI and 5-Year Survival Validation

A cohort study on the prognostic assessment of endometrial cancer patients based on the new FIGO staging system

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500104752
Enrollment
Unknown
Registered
2025-06-23
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

endometrial cancer

Interventions

Divided into Group A and Group B according to FIGO staging:NA

Sponsors

Shanghai General Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. The tumor specimens obtained from total hysterectomy or diagnostic dilation and curettage are reviewed by pathologists with at least 5 years of practice. Patients are diagnosed with endometrial cancer in accordance with the WHO Classification of Tumors of the Female Reproductive Organs (5th Edition). 2. The patient signs the informed consent form. 3. The patient has the conditions for follow-up.

Exclusion criteria

Exclusion criteria: Patients who are unable to undergo staged surgery due to the combination of severe internal and external diseases include the following cases: (1) Renal impairment; (2) Adrenal insufficiency; (3) Deep vein thrombosis or pulmonary embolism, thrombotic heart valve disease or thrombotic cardiac arrhythmia (e.g., subacute bacterial endocarditis with valve disease or atrial fibrillation); (4) Hereditary or acquired hypercoagulable states; (5) Severe cerebrovascular diseases or stroke; (6) Severe coronary heart disease or myocardial infarction; (7) Uncontrolled hypertension; (8) Severe diabetes with vascular complications.

Design outcomes

Primary

MeasureTime frame
The NRI assessment indicates that the FIGO 2023 staging system demonstrates improved discriminatory ability for 5-year overall survival (OS) in FIGO stage I-II endometrial cancer (EC) patients compare;

Secondary

MeasureTime frame
The NRI assessment demonstrates that the FIGO 2023 staging system improves the classification ability for predicting 3-year and 5-year PFS as well as 3-year OS in FIGO stage III-IV EC patients compare;

Countries

China

Contacts

Public ContactYang Ye

Shanghai General Hospital

ye.yang@shgh.cn+86 21 6324 0090

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026