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Effect of DL-3-n-butylphthalide on preventing ischemic cerebral vascular diseases in the patients with intracranial atherosclerotic stenosis, BUPICAS

Effect of DL-3-n-butylphthalide on preventing ischemic cerebral vascular diseases in the patients with intracranial atherosclerotic stenosis, BUPICAS

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500104739
Enrollment
Unknown
Registered
2025-06-23
Start date
2025-06-30
Completion date
Unknown
Last updated
2025-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intracranial artery stenosis

Interventions

Treatment group:0.2 g per dose, 3 times daily, DL-3-n-butylphthalide Basic drug therapy

Sponsors

PLA, Air Force Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >= 35 years old; 2.Intracranial artery stenosis >= 50%; 3.No use of NBP capsules or injections within 8 weeks; 4.Modified Rankin Scale (mRS) score <= 2; 5.Voluntary participation of the patient.

Exclusion criteria

Exclusion criteria: 1. Non-atherosclerotic cerebral arterial stenosis caused by diseases such as arterial dissection, vasculitis, moyamoya disease, reversible cerebral vasoconstriction syndrome, radiation vasculopathy, etc.; 2. Factors of cardiogenic emboli (such as atrial fibrillation, atrial myxoma, valvular heart disease, etc.); 3. Patients scheduled for interventional or surgical treatment; 4. Patients with severe psychological or mental diseases; 5. Pregnant women or lactating women; 6. Patients complicated with severe systemic diseases such as heart, respiratory, digestive system diseases, or tumors, with a life expectancy of less than 6 months; 7. Patients with abnormal liver and kidney functions; 8. Other conditions considered by researchers as inappropriate for inclusion.

Design outcomes

Primary

MeasureTime frame
Cerebral ischemic event;

Countries

China

Contacts

Public ContactChen Dawei

PLA ,Air Force Medical Center

cdw1975@163.com+86 135 5209 7551

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026