Respiratory failure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. age > 18 years old; 2. patients with type I respiratory failure requiring high-flow or noninvasive ventilation; 3. Informed consent was obtained;
Exclusion criteria
Exclusion criteria: 1.Patients with a history of neuromuscular disease, chronic pulmonary disease (e.g., moderate-to-severe restrictive or obstructive pulmonary disease), and cardiac or thoracic surgery; 2. Hypoxemia patients with emergency tracheal intubation; 3. Complicated with type II respiratory failure; 4. Patients who had received high-flow or non-invasive ventilation before admission. Patients with severe heart disease (such as severe heart failure, aortic valve stenosis, etc); 5. The quality of ultrasound images was poor, and the main data could not be obtained.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thickness of intercostal muscle;Diaphragm displacement;Diaphragm thickening score;Longitudinal strain of the diaphragm;Longitudinal strain of intercostal muscle;Tracheal intubation outcome event;Mechanical ventilation outcome event;Blood purification outcome event;Trachetecision outcome event;ECMO;Time of tracheal intubation;ICU length of stay;Mechanical ventilation time;Length of stay;Survival of ICU;Survival for 28 days;Height;Weight;Sex;Urine volume;Age;Pulmonary ultrasound parameters; | — |
Secondary
| Measure | Time frame |
|---|---|
| Parameters of oxygen therapy;Blood pressure;Heart rate;Blood oxygen saturation;Dosage of vasoactive drugs;Blood gas analysis;SOFA score;APACHEII score;Routine blood test;Clotting function;Biochemical indices;CRP;PCT;Breathing frequency;Troponin;B-type natriuretic peptide preformer;Body temperature;GCS core;CVP; | — |
Countries
China
Contacts
Yijishan Hospital of Wannan Medical College