open ocular trauma
Conditions
Interventions
Control group::Intravitreal injection of vancomycin
Test group:intravitreal injection of vancomycin combined with TA
Sponsors
Tianjin Medical University
General Hospital, Tianjin, China
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 18 and above; 2. Open ocular trauma, involving Zone III, with a high possibility of vitrectomy; 3. The first emergency surgery will be completed within 24 hours; 4. The patient voluntarily underwent a vitreoretinal surgery.
Exclusion criteria
Exclusion criteria: 1. Previous history of ocular trauma; 2. Previous history of ocular diseases such as glaucoma, uveitis, and vitreoretinal diseases; 3. Previous history of undergoing intraocular surgeries other than phacoemulsification for cataracts; 4. Patients who have previously or currently used high-dose corticosteroids; 5. Those who have adverse reactions to vancomycin and triamcinolone acetonide; 6. Patients with combined or highly suspected traumatic intraocular inflammation, intraocular foreign bodies, or optic canal fractures; 7. Patients who are pregnant or breastfeeding, have a history of mental illness, have a scarred constitution, and have severe systemic diseases; 8. For those who cannot undergo vitreoretinal surgery due to other reasons; 9. Those who cannot follow up regularly.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TPVR incidence and severity;Incidence of infectious endophthalmitis; | — |
Countries
China
Contacts
Public ContactHua Yan
Tianjin Medical University General Hospital, Tianjin, China
Outcome results
None listed