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To evaluate the safety and efficacy of radiofrequency treatment of postherpetic neuralgia with analgesic and sedative drugs

To evaluate the safety and efficacy of radiofrequency in the treatment of postherpetic neuralgia under comfortable conditions

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500104707
Enrollment
Unknown
Registered
2025-06-22
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postherpetic neuralgia

Interventions

Experimental group:Radiofrequency thermocoagulation of dorsal root ganglion under comfort treatment (sedation and analgesia)
Control group:Radiofrequency thermocoagulation of the dorsal root ganglion under local anesthesia

Sponsors

The First Affiliated Hospital of Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. After healing from shingles, the pain persists for more than 1 month; 2. Age> 18 years; 3. Pain level VAS score >=5; 4. Poor pain control with oral pregabalin or opioids. 5. Willing to undergo radiofrequency surgical treatment, clinical follow-up and truthful information.

Exclusion criteria

Exclusion criteria: 1. Have a pacemaker in the body; 2. Patients with severe chronic diseases that cause extremely poor physical condition, such as debilitating patients with advanced liver cirrhosis and extensive metastasis of cancer; 3. Coagulation abnormalities; 4. Infection in the body; 5. Pregnant women.

Design outcomes

Primary

MeasureTime frame
Mean arterial pressure;Heart rate (basal, preoperative, and 1min after RF start);

Secondary

MeasureTime frame
Intraoperative pain;Complications (nausea, vomiting, decreased heart rate, dizziness, discomfort, etc.);Postoperative satisfaction;

Countries

China

Contacts

Public ContactHuiyong Nie

The First Affiliated Hospital of Xi'an Jiaotong University

nhy19812000@stu.xjtu.edu.cn+86 29 85323215

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026