The Mechanism of TEAD4-TYMP Axis in Regulating Mitochondrial Gene Function Affecting Lymph Node Metastasis in Non-Small Cell Lung Cancer and the Surgical Treatment Strategy

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500104691

Enrollment

Unknown

Registered

2025-06-20

Start date

2024-08-08

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

Group with lymph node metastasis vs. Group without lymph node metastasis:No intervention

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with non-small cell lung cancer by pathology. 2. Age >= 18 years old. 3. Complete clinical data, including surgical records, pathological reports, imaging examination results, etc. 4. The patient or his/her family member has signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Combine with other malignant tumors. 2. Had received previous radiotherapy or chemotherapy to the chest. 3. Had severe functional impairments in important organs such as the heart, liver, and kidneys. 4. Refused to participate in this study or was unable to cooperate with the follow-up.

Design outcomes

Primary

Measure	Time frame
mRNA expression levels of TEAD4 and TYMP;disease free survival, DFS,OS;Overall Survival, OS;	—

Countries

China

Contacts

Public ContactJiang Weihua

The First Affiliated Hospital of Hebei North University

skypacer@163.com+86 138 3130 0110

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026