Pancreatic cancer
Conditions
Interventions
Gold Standard:The postoperative pathological diagnosis was pancreatic ductal adenocarcinoma
Index test:3D spatial contact characteristics of vascular-tumors based on deep learning algorithms
Sponsors
Changhai Hospital, The Navy Military Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Histologically confirmed diagnosis of PDAC; 2. Available preoperative contrast-enhanced CT scans with <=2 mm slice thickness, acquired within 30 days prior to surgery; 3. Underwent R0 or R1 surgical resection at Changhai Hospital between 2015 and 2019; 4. Documented pathological assessment of EPNI status; 5. Complete clinicopathological data available for model training and validation.
Exclusion criteria
Exclusion criteria: 1. Diagnosis of non-pancreatic primary tumors; 2. Presence of distant metastasis at the time of diagnosis; 3. CT image quality insufficient for segmentation (e.g., severe motion artifacts, slice thickness >2 mm); 4. Incomplete clinical, imaging, or histopathological records; 5. Cases involving synchronous malignancies or prior oncological treatments, except for patients receiving neoadjuvant therapy (who were included as a separate validation subgroup).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area Under the Receiver Operating Characteristic Curve, AUC;Sensitivity;Specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Negative predictive value (NPV);Positive predictive value (PPV); | — |
Countries
China
Contacts
Public ContactYun Bian
Changhai Hospital, The Navy Military Medical University
Outcome results
None listed