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Effect of intravenous lidocaine on intraoperative intracranial pressure and postoperative recovery quality during unilateral biportal endoscopic spinal surgery

Effect of intravenous lidocaine on intraoperative intracranial pressure and postoperative recovery quality during unilateral biportal endoscopic spinal surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500104665
Enrollment
Unknown
Registered
2025-06-20
Start date
2025-02-12
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar Disc Herniation

Interventions

Lidocaine group:Eligible patients were given intravenous lidocaine 1.5 mg/kg at anesthesia induction and lidocaine 1.5 mg/kg/h pumped during anesthesia maintenance
Control group:Normal saline

Sponsors

Ningbo Medical Centre Lihuili Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. ASAI.-II. 2. Age 40-80 years; 3. Exclusion criteria for patients with no obvious abnormalities in preoperative blood routine, liver and kidney function, electrolytes and coagulation function; 4. Obtain the patient's consent and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Patients allergic to lidocaine and related drugs; 2.Patients with a history of neurosurgery or ophthalmic surgery and/or a medical history related to high intracranial pressure or high intraocular pressure; 3.Patients with a history of spinal trauma or spinal surgery; 4.Patients who are unable to communicate and uncooperative.

Design outcomes

Primary

MeasureTime frame
ONSD/ETD;

Secondary

MeasureTime frame
Mean arterial blood pressure (MAP) and heart rate (HR);Intraoperative dosage of propofol and refine;Numeric Rating Scale;

Countries

China

Contacts

Public ContactXiaoyan Zhang

Ningbo Medical Centre Lihuili Hospital

1924978289@qq.com+86 574 55835827

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026