Diabetic retinopathy
Conditions
Interventions
Experimental group of PDR:NA
Control group of PDR:NA
Experimental group of NPDR:NA
Control group of NPDR:NA
Sponsors
Beijing Friendship Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: PDR sample collection: Experimental group: Only after being examined by 2 to 3 experienced ophthalmologists specializing in retinal diseases and having a clear diagnosis and staging can they be enrolled. The research subjects were patients with type 2 diabetes mellitus complicated with DR who underwent vitrectomy. Control group: Non-diabetic patients with simple rhegmatogenous retinal detachment, idiopathic macular hole and idiopathic epiretinal membrane and other diseases diagnosed by ophthalmologists specializing in retinal diseases, and who underwent vitrectomy. NPDR sample collection: Experimental group: Patients diagnosed with NPDR by fundus examination, over 18 years old, and planned to undergo cataract surgery. Control group: Patients with no abnormalities found in fundus examination, over 18 years old, and planned for cataract surgery.
Exclusion criteria
Exclusion criteria: Patients with a previous history of uveitis, glaucoma, optic neuropathy, high myopia, other retinal diseases, neurodegenerative diseases and infectious diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The expression levels of differentially expressed genes related to DR In fibrovascular membrane tissues;The expression levels of differential proteins and metabolites related to DR In the vitreous humor and aqueous humor; | — |
Countries
China
Contacts
Public ContactWang Yanling
Beijing Friendship Hospital, Capital Medical University
Outcome results
None listed