Surgical creation of a temporary stoma
Conditions
Interventions
Late Stoma Closure Group:None
Early Stoma Closure Group:None
Sponsors
The Third Affiliated Hospital Sun Yat-sen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients who underwent temporary ileostomy; 2.Patients in whom preoperative chest and abdominal CT and tumor marker tests ruled out tumor recurrence and distant metastasis; 3.Patients without significant stoma edema before closure; 4.Patients who requested stoma closure for various reasons and signed the surgical informed consent form;
Exclusion criteria
Exclusion criteria: 1.Patients with severe cardiopulmonary or cerebrovascular diseases who cannot tolerate reoperation; 2.Patients in whom preoperative tests revealed local tumor recurrence and distant metastasis; 3.Patients with marked colonic edema indicated by preoperative nutritional status assessment; 4.Patients with abdominal-wall defects or parastomal hernia requiring concurrent repair; 5.Patients requiring anastomotic reconstruction due to anastomotic stenosis or other related conditions;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal villus length in the ileal mucosa at the stoma site of patients;Microbial Flora Distribution in Patient Enema Solution or Feces;Paneth Cell Density in the Ileal Mucosal Layer at the Patient's Stoma Site;Intestinal crypt depth in the ileal mucosa at the stoma site of patients;Apoptotic Cell Density in the Ileal Mucosal Layer at the Patient's Stoma Site; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative Recovery Indicators of Patients;Serological Indicators of Intestinal Mucosal Function in Patients: Endotoxin, a1-Antitrypsin, Serum Amyloid A (SAA); | — |
Countries
China
Contacts
Public ContactWei Bo
The Third Affiliated Hospital Sun Yat-sen University
Outcome results
None listed