High Blood Pressure and Cognitive Impairment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 60 years or older 2. Completed more than six years of formal education 3. Newly diagnosed with stage 1 or 2 hypertension; or previously diagnosed hypertensive patients receiving antihypertensive medication 4. Willing to undergo cognitive assessment
Exclusion criteria
Exclusion criteria: 1. Inability to complete cognitive assessments due to visual/hearing impairments 2. Pre-existing dementia diagnosis or MMSE (Mini-Mental State Examination) score < 24 3. Alcohol abuse or current use of cognition-impairing medications (e.g., antihistamines, antipsychotics) 4. Clinically diagnosed depression or psychiatric disorders 5. History of Parkinson's disease, Alzheimer's disease, schizophrenia, or epilepsy 6. Cardiovascular/cerebrovascular events within 3 months or hospitalization for acute cardiocerebral diseases/surgeries 7. Failure to provide informed consent or concurrent participation in other clinical trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area under curve; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity; | — |
Countries
China
Contacts
Beijing Anzhen Hospital