Primary Angle-Closure Glaucoma
Conditions
Interventions
Control group:Phacoemulsification cataract extraction combined with intraocular lens implantation plus 360° goniosynechialysis.
Experimental group B:Phacoemulsification cataract extraction combined with intraocular lens implantation plus 360° goniosynechialysis and 120° goniotomy.
Experimental group C:Phacoemulsification cataract extraction combined with intraocular lens implantation plus 120° goniosynechialysis and 120° goniotomy.
Sponsors
Beijing Tongren Hospital
Eligibility
Sex/Gender
All
Age
45 Years to 79 Years
Inclusion criteria
Inclusion criteria: Patients with intermediate and advanced primary angle-closure glaucoma complicated with cataracts. 1. Age 45-79 years old, gender is not limited; 2. Meet the diagnostic criteria for intermediate and advanced PACG; 3. Those who have obvious cataract and corrected visual acuity <=0.5 (standard logarithmic visual acuity chart), or who need to undergo lens extraction as assessed by a clinician; 4. Intraocular pressure is difficult to control with drugs, and the disease continues to progress; 5. Informed consent of the patient, agreeing to cooperate with the follow-up.
Exclusion criteria
Exclusion criteria: 1. Previous history of intraocular surgery or ocular trauma (except laser iridotomy or laser iridoplasty); 2. Combined with other types of glaucoma, such as primary open-angle glaucoma, various types of secondary glaucoma (secondary angle-closure glaucoma, corticosteroid glaucoma, secondary glaucoma with angle regression, neovascular glaucoma, glaucoma secondary to inflammation, true microphthalmia and pseudoexfoliation syndrome, etc.); 3. Acute exacerbation of acute primary angle-closure glaucoma with uncontrolled inflammation; 4. Long-term use of topical or systemic glucocorticoids or combined with severe systemic diseases; 5. Patients with poor corneal condition, severe senile ring and gonioscopy before surgery who cannot see the structure of the angle; 6. Corrected visual acuity of the contralateral eye of the test eye is less than 0.05 (< 0.05).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraocular pressure;Types of anti glaucoma drugs; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cup to disk ratio;Retinal nerve fiber layer thickness;Mean defect;Peripheral anterior synechiae;Central anterior chamber depth;Best corrected visual acuity;Visual acuity; | — |
Countries
China
Contacts
Public ContactQiao Chunyan
Beijing Tongren Hospital
Outcome results
None listed