spontaneous intracranial hypotension syndrome
Conditions
Interventions
Sponsors
Zhongshan Hospital, Fudan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for spontaneous intracranial hypotension syndrome according to the International Classification of Headache Disorders, 3rd edition (ICHD-3); 2. Received continuous epidural injection of HES therapy at Zhongshan Hospital Affiliated to Fudan University from January 2020 to December 2024; 3. Complete follow-up data: Have complete clinical medical records, imaging examination data and at least 3 months of follow-up records; 4. Voluntary participation: Patients or their families give informed consent to the study.
Exclusion criteria
Exclusion criteria: 1.Concomitant neurological disorders??: Intracranial space-occupying lesions, cerebrovascular diseases, intracranial infections, etc; 2.Severe systemic diseases??: Severe cardiac, hepatic, or renal dysfunction, coagulation disorders, etc., which may affect treatment efficacy or safety assessment; 3.??Prior cranial/spinal surgery??: History of craniotomy or spinal surgery that may interfere with spontaneous intracranial hypotension (SIH) diagnosis or treatment evaluation; 4.Non-standard treatment: such as conservative treatment not lasting enough time (at least 2 weeks) or EBP/HES treatment Not operating as standard; 5.Insufficient follow-up??: Follow-up duration <3 months, precluding long-term efficacy evaluation; 6.Other types of intracranial hypotension??: Traumatic or iatrogenic intracranial hypotension.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Treatment success rate (complete symptom relief and/or improvement in imaging evidence); | — |
Secondary
| Measure | Time frame |
|---|---|
| Headache severity (VAS score);Symptom relief time (headache relief time, disappearance time of accompanying symptoms);Recurrence rate (symptom recurrence during follow-up period);Infection after EBP surgery; | — |
Countries
China
Contacts
Public ContactMiao Changhong
Zhongshan Hospital, Fudan University
Outcome results
None listed