None
Conditions
Interventions
0.4mg/kg Esketamine Group:Esketamine
0.1 mg/kg Esketamine Group:Esketamine
0.2 mg/kg Esketamine Group:Esketamine
0.3mg/kg Esketamine Group:Esketamine
0 mg/kg Esketamine Group:Esketamine
Sponsors
Women and Children’s Hospital of Ningbo University
Eligibility
Sex/Gender
Female
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1.Female patients scheduled for hysteroscopy under intravenous anesthesia; 2.Age 18~55 years old; 3.ASA I~II; 4.BMI 19~26 kg/m^2; 5.Mallampati I~II;
Exclusion criteria
Exclusion criteria: 1.history of severe hypertension, elevated eye pressure, or increased intracranial pressure risks; 2.Pregnancy; 3.history of hyperthyroidism; 4.neurological and psychiatric disorders; 5.High-risk for reflux and aspiration; 6.history of allergy to ketamine or propofol; 7.addicted to opioids or other drugs;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The half-effective effect chamber concentration of propofol for inhibiting cervical dilation response; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total consumption of propofol;Anesthesia recovery time; | — |
Countries
China
Contacts
Public ContactShen Yanping
Women and Children’s Hospital of Ningbo University
Outcome results
None listed