Postoperative delirium
Conditions
Interventions
Perioperative Optimization Strategy Group:Implement temperature monitoring, anesthesia depth monitoring, blood protection, multimodal analgesia, psychological guidance, sleep guidance
Conventional Perioperative Care Group:Conventional management
Sponsors
The Second Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) age >=60 years, regardless of sex, scheduled for elective orthopedic surgery; (2) ASA physical status classification I–III; (3) BMI 18–30 kg/m²; (4) preoperative Montreal Cognitive Assessment (MoCA) score >=26, with patients exhibiting pre-existing cognitive impairment excluded.
Exclusion criteria
Exclusion criteria: (1) preoperative diagnosis of Alzheimer's disease or other neurodegenerative diseases; (2) severe cardiopulmonary dysfunction, language or hearing impairment precluding assessment; (3) a history of severe allergic reactions to anesthetic agents; (4) other conditions deemed unsuitable for inclusion by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Demographic information;ast medical history;Psychological status assessment;Preoperative cognitive function assessment;Preoperative quality of life assessment;Preoperative biomarkers;Surgical information;Anesthesia information;Intraoperative monitoring;Postoperative delirium assessment;Pain assessment;Postoperative quality of life assessment;Sleep quality assessment;Postoperative biomarkers; | — |
Countries
china
Contacts
Public ContactMinghui Li
The Second Affiliated Hospital of Guangxi Medical University
Outcome results
None listed