None (Young college students aged 18 - 22)
Conditions
Interventions
Blank control group:Participants will not undergo any exercise intervention. During the trial period, they are required to maintain regular sleep schedules and follow dietary restrictions, such as avo
Morning exercise group:Run for exercise between 7:30 and 10 o clock in a well - lit environment. It is moderate - intensity exercise at 50% - 65% of the maximum oxygen uptake, carried out 4 times a we
Evening exercise group:Run for exercise between 19:00 and 22:00 in a dark environment.It is moderate - intensity exercise at 50% - 65% of the maximum oxygen uptake, carried out 4 times a week, 45 minu
Sponsors
Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 24 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: Age: Adults aged 18–24 years. BMI: Body Mass Index (BMI) between 18 and 18–24. Lifestyle: Sedentary lifestyle (defined as lacking regular exercise or having low daily physical activity). Health Status: No metabolic diseases (e.g., diabetes), acute illnesses, or severe chronic conditions (e.g., cardiovascular diseases, respiratory disorders, musculoskeletal issues). Diet & Medication: Maintained a similar dietary structure for at least one month prior to the study, with no probiotic supplementation or use of antibiotics/other medications that may affect gut microbiota. Informed Consent: All participants must provide signed informed consent. Gender Balance: Equal representation of males and females. Gastrointestinal Symptoms: Baseline Gastrointestinal Symptom Rating Scale (GSRS) score within normal or mild range (score = 3).
Exclusion criteria
Exclusion criteria: Exclusion Criteria: 1.Health Conditions: Acute illnesses (e.g., cerebral hemorrhage, acute myocardial infarction, asthma attacks). Severe complications (e.g., pulmonary infections, newly developed deep vein thrombosis). Poorly controlled chronic diseases (e.g., heart disease, diabetes, asthma). Cardiovascular diseases (e.g., angina, arrhythmia, valvular heart disease). Respiratory disorders (e.g., COPD, interstitial lung disease). Musculoskeletal issues (e.g., osteoporosis, unhealed fractures, arthritis). 2.Lifestyle Habits: Regular consumption of caffeine or alcoholic beverages. Abnormal food intake, appetite disorders, or recent medication use. Recent (within 2 months) use of antibiotics, prebiotics, probiotics, or symbiotic therapies. 3.Medical History: Genetic disorders, active autoimmune diseases, chronic illnesses, diabetes, or acute diseases. Required bed rest or participation in high-intensity sports programs within the past 3 months. Major inflammatory gastrointestinal disorders, eating disorders, hypothyroidism, or other endocrine diseases. 4.Other: Females during menstruation (participation paused during this period). GSRS score >= 4 (moderate to severe symptoms). Inability to comply with study requirements (e.g., altering diet or exercise habits).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Physical Activity Level - International Physical Activity Questionnaire(IPAQ);Mental Health - Depression Anxiety Stress Scales (DASS);Physical Fitness and Health - National Physical Fitness Assessment Standards (Revised in 2023);Sleep Quality - Pittsburgh Sleep Quality Index (PSQI);Gut microbiota - 16S third - generation gut microbiota sequencing; | — |
Countries
China
Contacts
Public ContactLiu Guochun
School of Sports Medicine, Chongqing Medical University
Outcome results
None listed