Mild Cognitive Impairment
Conditions
Sponsors
Xuanwu Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients over 65 years old, Han ethnicity from northern China, ASA classification I~III; 2. Mild cognitive impairment before surgery; 3. Undergoing elective abdominal surgery under general anesthesia with a surgical duration >= 2 hours; 4. Written informed consent form;
Exclusion criteria
Exclusion criteria: 1. History of ischemic cerebrovascular disease; 2. Dementia, epilepsy, PD, schizophrenia and other neurological and psychiatric disorders; 3. Abnormal coagulation function and high bleeding risk; 4. Inserting a cardiac pacemaker or a metal implant in the brain; 5. History of surgery above the T7 vertebra level and presence of metal implants; 6. Communication difficulties caused by visual or hearing impairments; 7. Participate in another intervention study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neuropsychological scale (MOCA); | — |
Secondary
| Measure | Time frame |
|---|---|
| a oscillation parameters (peak frequency, connectivity);length of stay;Inflammatory factors and markers related to neuroinflammation and nerve injury;perioperative sleep quality;incidence of POD;incidence of dNCR;incidence of perioperative anxiety;Adverse event;Neuropsychological scale (MOCA);Complications of other systems;postoperative pain; | — |
Countries
China
Contacts
Public ContactTianlong Wang
Xuanwu Hospital Capital Medical University
Outcome results
None listed