Healthy volunteers – Muscle adaptation
Conditions
Interventions
AM_ resistance exercise group:Standardized lower-limb resistance training (3 sessions/week for 4 weeks), starting daily at 8:00 AM
PM_ resistance exercise group:Standardized lower-limb resistance training (3 sessions/week for 4 weeks), starting daily at 6:00 PM
Sponsors
Key Laboratory of Adolescent Health Assessment and Exercise Intervention of Ministry of Education, College of Physical Education and Health, East China Normal University, Shanghai 200241, PR China
Eligibility
Sex/Gender
Male
Age
18 Years to 30 Years
Inclusion criteria
Inclusion criteria: Healthy males aged 18–30 years; Currently enrolled university students with good compliance; No history of chronic diseases, metabolic disorders, or musculoskeletal injuries; No participation in any systematic resistance training or competitive sports within the past two months; No history of smoking or excessive alcohol consumption; Willing to participate in the study and provide written informed consent.
Exclusion criteria
Exclusion criteria: History of cardiovascular disease, hypertension, diabetes, hepatic or renal dysfunction, or major metabolic disorders; Presence of musculoskeletal disorders or injuries that impair exercise performance; Use of medications or nutritional supplements (e.g., protein powder, creatine, caffeine) within the past 2 months; Incomplete participation in the full training protocol; Failure to complete post-training sampling or refusal to provide blood samples; Voluntary withdrawal or dropout during the study period.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Plasma Proteomics Profile;Plasma Metabolomics Profile;Plasma Transcriptomic Features (RNA-seq); | — |
Primary
| Measure | Time frame |
|---|---|
| Maximal Leg Flexion and Extension Strength; | — |
Countries
China
Contacts
Public ContactJian Lu
Key Laboratory of Adolescent Health Assessment and Exercise Intervention of Ministry of Education, College of Physical Education and Health, East China Normal University, Shanghai
Outcome results
None listed