herpes zoster
Conditions
Interventions
Control group (PRF):Received only radiofrequency ablation
Ozone group (PRF + ozone):Localized ozone injection after radiofrequency ablation therapy
PRP group (PRF+PRP):Local injection of PRP after radiofrequency ablation 2-3ml
Sponsors
Changzhi People's Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 40-80 years old and gender; 2. Meet the International Academy of Pain (IASP) diagnostic criteria for postherpetic neuralgia (PHN); 3. Duration of disease >= 3 months; 4. No pain relief by conservative methods such as oral pregabalin and other medications before surgery; 5. Absence of severe organ dysfunction; 6. Ability to objectively assess perceived pain and complete follow-up visits; 7. Agree to participate in this study and are able to sign an informed consent form; 8. Not participating in other clinical trials;
Exclusion criteria
Exclusion criteria: 1. Coagulation disorders, immune system disorders, active infections, history of severe drug allergies; 2. Pregnant or lactating females; 3. Previous treatment with similar interventions; 4. Refusal to participate, uncooperative behavior and intellectual inability to complete self-assessment questionnaires; 5. Contraindications to ozone injection and PRP injection; 6. Severe cardiopulmonary disease, hepatic or renal insufficiency or any serious life-threatening disease; 7. Patients with spinal deformity or a history of spinal surgery that affects CT localization;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analog Scale (VAS);Pittsburgh Sleep Quality Index (PSQI);Quality of life score (SF-14 scale); | — |
Secondary
| Measure | Time frame |
|---|---|
| Post-treatment painkiller use;gender;age;Body Mass Index (BMI); | — |
Countries
China
Contacts
Public ContactWu Jie
Changzhi People's Hospital Affiliated to Changzhi Medical College
Outcome results
None listed