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A Randomized, Double-Blind, Controlled Clinical Trial Evaluaing the Efficacy and Safety of Remimazolam-Alfentanil and Ciprofol-Alfentanil for Painless Fiberoptic Bronchoscopy

A Randomized, Double-Blind, Controlled Clinical Trial Evaluaing the Efficacy and Safety of Remimazolam-Alfentanil and Ciprofol-Alfentanil for Painless Fiberoptic Bronchoscopy

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500104535
Enrollment
Unknown
Registered
2025-06-18
Start date
2025-06-23
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Remimazolam group:Anesthesia Induction: Alfentanil 6 µg/kg + Remimazolam 0.2 mg/kg Anesthesia Maintenance: Remimazolam 1 mg/kg.h
Ciprofol group:Anesthesia Induction: Alfentanil 6 µg/kg + Ciprofol 0.4 mg/kg Anesthesia Maintenance: Ciprofol 1 mg/kg.h

Sponsors

Xiangya Hospital, Central South University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients scheduled for painless fiberoptic bronchoscopy in our hospital; 2.No history of anaesthetic allergy; 3.No recent use of sedatives and analgesics; 4.Patients and family members were informed and consented to the study.

Exclusion criteria

Exclusion criteria: 1.Respiratory failure(PaO250mmHg); 2.NYHA Class IV, severe arrhythmias, and structural heart disease; 3.acute cerebral infarction or cognitive/mental disorders; 4.Liver function: Child-C or chronic kidney disease:CKD stage 4-5; 5.communication difficulties; 6.abnormal coagulation function; 7.difficult airway; 8.Pregnant women and nursing patients.

Design outcomes

Primary

MeasureTime frame
Anesthesia Induction Success Rate;Incidence of Intraoperative Hypotention;Incidence of Intraoperative Hypoxemia;

Secondary

MeasureTime frame
Patient satisfaction score;Pain Numeric Rating Scale (NRS);Operator satisfaction score;Adverse Reaction Incidence Rate;

Countries

China

Contacts

Public ContactYang Yong

Xiangya Hospital, Central South University

yangwulf@163.com+86 138 7315 1125

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026