Acute myocardial infarction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adults aged 30–79 years; 2. Estimated 10-year ASCVD risk >=20% based on China-PAR; 3. Permanent residency in the study region (>=6 months/year); 4. Ability to provide written informed consent; 5. Willingness to participate in repeated data and biospecimen collection.
Exclusion criteria
Exclusion criteria: 1. History of acute myocardial infarction or coronary revascularization; 2. Terminal illness with life expectancy <1 year; 3. Severe psychiatric or cognitive impairment precluding protocol adherence; 4. Current pregnancy or breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lipoprotein-associated phospholipase A2 (Lp-PLA2);Soluble growth - stimulation expressed gene 2 protein (sST2);myeloperoxidase(MPO);Heart-type fatty acid-binding protein (H-FABP);N-terminal pro-brain natriuretic peptide (NT-proBNP);Creatine kinase-MB (CK-MB);High-sensitivity cardiac troponin T(hs-cTnT); | — |
Secondary
| Measure | Time frame |
|---|---|
| High-sensitivity C-reactive protein (hs-CRP);Related indicators of dynamic electrocardiogram monitoring equipment;Indicators related to echocardiogram;area under the curve; AUC;sensitivity;specificity; | — |
Countries
China
Contacts
Gansu Provincial Hospital