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Multimodal Radiomics-Based Models for Early Diagnosis and Prognostic Prediction in Oral Tongue Squamous Cell Carcinoma

Non-invasive Preoperative Prediction Model and Prognostic Survival Model for Tumor Budding in Oral and Head-Neck Cancer Based on Multimodal Data

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500104507
Enrollment
Unknown
Registered
2025-06-18
Start date
2025-08-01
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral tongue squamous cell carcinoma

Interventions

Observation group:None

Sponsors

Nanfang Hospital, Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years; 2. Gender: Any; 3. Received treatment at Nanfang Hospital, Southern Medical University from July 2018 to January 2023, with no further visits after January 2023 (lost to follow-up); 4. Underwent surgery for oral/head and neck cancer; 5. Had preoperative CT/MRI/PET-CT imaging at Nanfang Hospital, Southern Medical University; 5. Underwent postoperative pathological examination at Nanfang Hospital, Southern Medical University.

Exclusion criteria

Exclusion criteria: 1. Patients who underwent oral/head and neck cancer surgery at hospitals other than Nanfang Hospital, Southern Medical University. 2. Patients without CT/MRI/PET-CT imaging from Nanfang Hospital, Southern Medical University. 3. Patients deemed ineligible for participation in this study by the investigator (e.g., due to incomplete records, poor general condition, or other clinical concerns).

Design outcomes

Primary

MeasureTime frame
Tumor Budding;Disease free survival;Overall survival;Receiver Operating Characteristic curve;Sensitivity;Specificity;Area under the curve;C-index;—

Countries

China

Contacts

Public ContactXiqiang Liu

Nanfang Hospital, Southern Medical University

liuxiqiang@smu.edu.cn+86 186 8886 2086

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026