Liver diseases
Conditions
Interventions
Liposomal Bupivacaine-Applied External Oblique Intercostal Plane Block Group:After the patient was under general anesthesia, ultrasound-guided external oblique intercostal plane (EOIP) block was perf
Ropivacaine-Applied External Oblique Intercostal Plane (EOIP) Block Group:After the patient was under general anesthesia, ultrasound-guided external oblique intercostal plane (EOIP) block was performe
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Patients scheduled for elective partial hepatectomy under general anesthesia; (2) No gender restriction; Aged 18-65 years; BMI 18.5-28 kg/m²; ASA (American Society of Anesthesiologists) class I or II; (3) Provision of written informed consent; (4) Normal preoperative cardiac, hepatic, pulmonary, and renal function in all patients; (5) Intact cognitive function.
Exclusion criteria
Exclusion criteria: (1) Patients with anatomic abnormalities or a history of previous upper abdominal surgery; (2) Infection at the puncture site; (3) Coagulopathy or platelet disorders; history of bleeding tendency or hematologic diseases; (4) Concurrent surgery at other sites; (5) Allergy to local anesthetics; (6) Chronic use of analgesics; (7) Severe respiratory or cardiovascular diseases; (8) Severe hepatic or renal dysfunction; (9) Preoperative impairment of consciousness or cognitive dysfunction;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative opioid consumption within 72 hours postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Highest reported resting and coughing NRS pain scores in the PACU;Resting and coughing NRS pain scores at 4h, 8h, 16h, 24h, 48h, and 72h postoperatively Key refinements;Time to first rescue analgesia postoperatively;Number of rescue analgesia administrations, analgesic types, and total dosages within 72 hours postoperatively;Time to first PCA demand and total number of effective demands within 72 hours postoperatively;Heart rate (HR) and blood pressure (BP) at the following time points: Pre-induction of general anesthesia ,Surgical incision ,1 hour after surgery commencement;Total intraoperative opioid consumption;QoR-15 scores at preoperative 24h, postoperative 24h, 48h, and 72h;PSQI scores on the day before surgery, the day of surgery, and the second day after surgery;Time to first flatus and ambulation after surgery; | — |
Countries
China
Contacts
Public ContactZhang Xuekang
The First Affiliated Hospital of Nanchang University
Outcome results
None listed