None listed
Conditions
Interventions
Test group :Participants will orally take the investigational product(GeneIII? L-Ergothioneine Capsules) continuously for three menstrual cycles, with administration recorded in patient diaries.
Sponsors
Qingdao Central Hospital, University of Health and Rehabilitation Sciences
Eligibility
Sex/Gender
Female
Age
35 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1.Females aged 35-40 years (inclusive); 2.Menstrual disorders including oligomenorrhea, polymenorrhea, prolonged/shortened cycles, amenorrhea, irregular menstrual flow, or dysmenorrhea; 3. Biochemically confirmed anti-Müllerian hormone (AMH) level <1.68 ng/mL; 4.Voluntary provision of written informed consent;
Exclusion criteria
Exclusion criteria: 1. Patients with severe primary diseases involving cardiovascular, hepatic, renal, pulmonary, biliary, hematopoietic systems, or malignant tumors; psychiatric disorders; 2. Individuals with hyperallergenic constitution or known allergies/contraindications to the investigational product; 3. History of oophorectomy or other ovarian reserve-compromising surgeries; 4. Endocrine disorders affecting ovulation including PCOS, hyperprolactinemia, hyperandrogenism, diabetes, or thyroid/adrenal dysfunction; 5. Pregnant or lactating women; 6. Alcohol abuse (>14 units/week; 1 unit ˜ 285mL beer/25mL spirits [40%]/100mL wine) or history of substance abuse; 7. Laboratory abnormalities at screening meeting any of: (1). White blood cell count (WBC) 2×ULN (Upper Limit of Normal) (4). Serum creatinine >1.5×ULN 8. Participation in other clinical trials within 30 days, or systemic use of interfering medications/products (e.g., vitamins/antioxidants, hormonal agents); 9. Investigator-determined ineligibility or inability to complete the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in Serum Anti-Müllerian Hormone (AMH) Levels; | — |
Countries
China
Contacts
Public ContactLiu Fengjuan
Qingdao Central Hospital, University of Health and Rehabilitation Sciences
Outcome results
None listed