Esophageal cancer
Conditions
Interventions
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Scheduled for elective minimally invasive Mckeown esophagectomy under general anesthesia; (2) Age >= 18 years; (3) American Society of Anesthesiologists (ASA) physical status classification I-III; (4) Provision of written informed consent.
Exclusion criteria
Exclusion criteria: (1) Contraindications to regional anesthesia (e.g., coagulopathy, infection at the puncture site); (2) Known allergy or contraindication to the study medications; (3) History of spinal deformity or spinal surgery; (4) History of chronic pain requiring regular opioid analgesia; (5) Inability to comprehend the study questionnaires/scales
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Overall Benefit of Analgesia Score (OBAS) at 24 h postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative pain on postoperative days (POD) 1-3 and 7;Time to first analgesic request, number of patients requiring rescue analgesia and total rescue analgesic consumption;Number of demands and total drug consumption from the intravenous patient-controlled analgesia (PCA) pump;Total analgesic consumption;Quality of Recovery (QoR) scores on postoperative days (POD) 1-3 and 7;Block procedure time, dermatomal spread of the block, and block duration;Anxiety and depression scores on POD 1-3 and 7;Patient satisfaction;Time to first ambulation, first flatus, first defecation, and first oral intake;Days Alive at home in the 30 days after Surgery;Length of postoperative hospital stay;30-day all-cause mortality and readmission rates; | — |
Countries
China
Contacts
Public ContactYu Hai
West China Hospital of Sichuan University
Outcome results
None listed