Interventional therapy for tumors
Conditions
Interventions
Intervention group:Cyclopofol+Alfentanil
ci-Profol:Propofol+Alfentanil
Sponsors
Lishui Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients who intend to undergo tumor interventional therapy; 2. Age> = 18 years old, gender is not limited; 3. ASA is graded as Grade II~III.; 4.18Kg/m^2<=BMI<=25kg/m^2; 5. Clearly understand and voluntarily participate in the study, and sign the informed consent form by themselves or their family members.
Exclusion criteria
Exclusion criteria: 1. Patients with severe respiratory insufficiency, obstructive pulmonary disease, history of bronchospasm requiring treatment in the past 3 months, acute respiratory infection within 1 week, and obvious symptoms such as fever, wheezing, nasal congestion and cough; Proposed endotracheal intubation for general anesthesia; 2. Have serious heart diseases such as severe arrhythmia, heart failure, unstable angina, severe myocardial infarction in the past 6 months, severe heart valve disease, etc.; 3. History of severe cerebrovascular disease and epilepsy; 4. Patients with severe liver and kidney dysfunction; 5. Patients who are allergic to propofol or cyclopofol; 6. People with communication difficulties such as schizophrenia and intellectual disability; 7. Other conditions judged by the investigator to be unsuitable for inclusion in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence rate of adverse events related to the respiratory system (respiratory depression, apnea, hypoxia); | — |
Secondary
| Measure | Time frame |
|---|---|
| Research drug use;Evaluation of cyclopofol compared with propofol in tumor interventional therapy: Hypotension requiring intervention (SBP <) 90mmHg or a 30% decrease from the baseline with a duration of more than 2 m;Duration of full consciousness ;The occurrence and severity of nausea and vomiting;Sedation/anesthesia satisfaction evaluation;Safety evaluation; | — |
Countries
China
Contacts
Public ContactHao Cheng
Lishui Central Hospital
Outcome results
None listed