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The influence of different concentrations of lidocaine combined with ropivacaine on epidural-related maternal fever during labor analgesia.

The influence of different concentrations of lidocaine combined with ropivacaine on epidural-related maternal fever during labor analgesia.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500104424
Enrollment
Unknown
Registered
2025-06-17
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fever during the labor process

Interventions

Group L2R:Labor analgesia mainly consisting of lidocaine at 0.25%, ropivacaine at 0.1% and sufentanil at 0.33 ug/ml.
Group L1R:Labor analgesia mainly consisting of lidocaine at 0.5%, ropivacaine at 0.1% and sufentanil at 0.33 ug/ml.
Group R:Labor analgesia mainly based on 0.125% ropivacaine and 0.33 ug/ml of sufentanil

Sponsors

The Women and Children's Hospital Affiliated to Ningbo University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Primiparas, full-term (gestational weeks 37-42), singlet pregnancies, confirmed as head position delivery by prenatal ultrasound examination, aged 20-40 years, cervical dilation 2-5 cm, the white blood cell (WBC) and hemoglobin (Hb) levels of the parturient are within the normal range, and the body temperature measured by an ear thermometer (eardrum temperature <38.0?).

Exclusion criteria

Exclusion criteria: Contraindications for any nerve block anesthesia, women with infectious diseases, premature rupture of membranes, as well as gestational hypertension, gestational diabetes, and gestational thyroid diseases, etc

Design outcomes

Primary

MeasureTime frame
The incidence of ERMF;

Secondary

MeasureTime frame
NRS pain score;Bursting pain;Apgar score;

Countries

China

Contacts

Public ContactYan Haiya

The Women and Children's Hospital Affiliated to Ningbo University

nbyanhaiya@sina.com+86 138 6789 5475

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026