overweight or obesity
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Aged >=18 years and =1 year with no plans for extended absence (>4 weeks) during the study period (4) Neither pregnant nor lactating (5) No plans for anti-obesity medication or bariatric surgery within 2 years (6) Willing to provide written informed consent
Exclusion criteria
Exclusion criteria: (1) History of malignancy (except locally cured basal cell carcinoma) (2) Clinically diagnosed psychiatric disorders (e.g., major depressive disorder requiring pharmacotherapy) (3) Severe comorbidities or functional impairments preventing completion of study procedures (4) Current participation in weight management clinical trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body Weight; | — |
Secondary
| Measure | Time frame |
|---|---|
| Body mass index;Obesity rate;Body fat percentage;Body composition;Blood pressure;Blood routine;liver function;Renal function;Inflammatory factor;Blood glucose (fasting blood glucose, glycated hemoglobin);Pancreas islet function;Hormone;Metabolome;Intestinal flora;Urine routine;Urinary chemistry (urinary creatinine, urinary microalbumin);Lifestyle (diet, physical activity, smoking, alcohol, sleep);Mental and psychological states (depression, anxiety, stress);Appetite;Self-efficacy;Health economics indicators;Implemental indicators (fidelity, adoption, other implemental indicators);blood lipid; | — |
Countries
China
Contacts
School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.