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Application Research of Extracorporeal Diaphragm pacing Combined with pulmonary Rehabilitation in Improving Pulmonary Function of Patients with Advanced lung Cancer

Research on the Improvement of Pulmonary Function in Patients with Advanced Lung Cancer by Individualized Pulmonary Rehabilitation Combined with External diaphragm pacing Technologyr

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500104416
Enrollment
Unknown
Registered
2025-06-17
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

Control group:While undergoing immunotherapy, routine medical care for thoracic oncology is provided.
Intervention group:On the basis of routine care and immunotherapy, the external diaphragm pacing technique combined with the pulmonary rehabilitation program was implemented.

Sponsors

Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Histological examination confirmed the primary lung cancer. 2. Patients diagnosed as stage III or IV of lung cancer according to the eighth edition of the TNM staging system for lung cancer, who are not suitable for surgical resection and require immunotherapy; 3. The patient is aware of his or her diagnosis and condition. 4. The presence of dyspnea symptoms =1 point as detected by the mMRC Dyspnea Index Scale; 5. Pulmonary function tests showed that the ratio of forced expiratory volume in one second (FEV1) to forced vital capacity (FVC) was less than 70%.

Exclusion criteria

Exclusion criteria: 1. Severe anemia, myelosuppression or extensive metastasis that cannot be tolerated; 2. Patients with severe physical activity limitations who need to rest in bed; 3. Those with cognitive or mental disorders or physical functional disorders who are unable to cooperate; 4. Combined with severe hypertension, coronary heart disease and asthma. 5. The attending physician deems it unsuitable to participate in the research.

Design outcomes

Primary

MeasureTime frame
pulmonary function;

Secondary

MeasureTime frame
Six-minute walking test distance;quality of life;

Countries

China

Contacts

Public ContactZhu Fang

Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital

13960929872@163.com+86 139 6092 9872

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026