myasthenia gravis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients who seek treatment at the First Affiliated Hospital of Chongqing Medical University and have fluctuating skeletal muscle weakness and at least one of the following three conditions will be included: Positive response to cholinesterase inhibitors; repetitive electrical stimulation shows decreasing frequency and positive AChR or muscle-specific kinase (MuSK) antibodies;
Exclusion criteria
Exclusion criteria: 1.Patients with lung disease or heart failure, or a history of non-invasive ventilator or tracheotomy;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diaphragm thickness; | — |
Secondary
| Measure | Time frame |
|---|---|
| QMG;dose of immunosuppressants;Respiratory infection occurred within 6 months;Diaphragmatic excursion;Diaphragmatic elasticity;blood gas analyses;Complete Blood Count; | — |
Countries
China
Contacts
The First Affiliated Hospital of Chongqing Medical University