Acute Respiratory Distress Syndrome
Conditions
Interventions
Conventional group:Supine position during SBT
Semi-recumbent group:Semi-recumbent position during SBT
Sitting group:Sitting position during SBT
Sponsors
The Second Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. ARDS patients with mechanical ventilation whose condition has been relieved or improved; 2. The patient is awake and has the effort of self-inspiration; 3. Sao 2 > 90%, FiO2=5mL/kg, no obvious acidosis; 5. Hemodynamic stability, systolic blood pressure of 90-160mmHg, no vasoactive drugs or low-dose pressor (dobutamine < 5 µ g/kg/min or norepinephrine < 0.15 µ g/kg/min), and heart rate <=140 beats/min; 6. No fever, anemia, good mental state, etc.
Exclusion criteria
Exclusion criteria: 1. Age < 18 years old; 2. Pregnancy and severe obesity; 3. There are contraindications for EIT such as rib fracture, chest and hand; 4. ICU stay time <=48 hours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ventilation blood flow ratio;Shunt rate;Dead space rate;Region of interest; | — |
Secondary
| Measure | Time frame |
|---|---|
| Plateau pressure;Lung compliance;Diaphragm activity;Diaphragmatic thickening fraction; | — |
Countries
China
Contacts
Public ContactRuyang Xiong; Zheng Junbo
The Second Affiliated Hospital of Harbin Medical University
Outcome results
None listed