Low Anterior Resection Syndrome
Conditions
Interventions
Treatment group:sacral neuromodulation
Sponsors
The Second Hospital of Jilin University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Over 18 years old, gender not limited; (2) Previously diagnosed with rectal cancer, the tumor location was less than 5cm away from the anus, and underwent radical anterior resection of rectal cancer (intraoperative radiotherapy); (3) The LARS score was >=29 points during the 7-day screening period; (4) The anal sphincter was retained during the operation and the continuity of the rectum was intact. (5) Voluntarily participate in this clinical study. Before the start of the study, the subjects sign the written informed consent form. (6) After enrollment, it was agreed not to increase or decrease the related drugs that affect LARS symptoms and pelvic function at will during the trial period; (7) Be able to communicate well with the researcher and be willing to follow the entire trial requirements.
Exclusion criteria
Exclusion criteria: (1) Combined with irritable bowel syndrome, inflammatory bowel disease, active perianal abscess or anal fistula, severe rectal prolapse, and repeated intestinal infections; (2) Those who have received radiotherapy before radical surgery; (3) The time for radical surgery/preventive stoma reduction surgery is less than 12 months; (4) Those who undergo radical surgical resection of intestinal segments other than the rectum; (5) Patients with permanent stoma; (6) Tumor recurrence and metastasis occurred during the follow-up period of the tumor; (7) Pregnant and lactating women; (8) Mental disorders can not cooperate with doctors; (9) There are concomitant diseases that seriously affect health; (10) Other circumstances where the researcher deems it inappropriate to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Therapeutic efficiency; | — |
Secondary
| Measure | Time frame |
|---|---|
| LARS score;Wexner score;FIQoL Score;Efficacy satisfaction;Bowel diary; | — |
Countries
China
Contacts
Public ContactMin Wang
The Second Hospital of Jilin University
Outcome results
None listed